Chlorhexidine gluconate

  • Reviewed Sep 27, 2026
  • Checked against CDC & WHO

Chlorhexidine gluconate (CHG), often just called chlorhexidine, is an antiseptic that kills a broad range of bacteria and some viruses and fungi. Unlike alcohol, it binds to the skin and keeps working for hours, which is why it is used in surgical hand scrubs, antiseptic hand washes, skin preparation before surgery, patient bathing wipes, and prescription mouthwash for gum disease. Some lotions can reduce its effect, so healthcare workers should use lotions approved by their facility.

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