The cost of a hand hygiene program
Hospital budgets are tight. Here’s the case that a hand hygiene program pays for itself, with the numbers to back it up.
The problem, in numbers
- 1 in 38
U.S. hospital patients had a healthcare-associated infection on a given day in 2023.
CDC, 2026 - 518,000
Estimated HAIs in U.S. hospitals in 2023.
CDC, 2026 - $1.7 billion
Estimated U.S. healthcare cost of MRSA alone in 2017.
CDC, 2019 - 1 in 10
Patients who get an HAI die from it, on average, worldwide.
WHO, 2022
What one state found
Pennsylvania was one of the first states to publish hospital infection data. Its 2006 report found that patients who picked up an infection in the hospital were far more likely to die, stayed in the hospital much longer, and ran up far higher charges: an average of about $176,000, against about $33,000 for patients without an infection. The exact figures are dated, but the pattern holds: infections are among the most expensive complications a hospital can have.
Does a program actually work?
Yes. The best-known example is Geneva University Hospitals, where a hospital-wide campaign raised hand hygiene compliance from 48% to 66%. Over the same period, the share of patients with a hospital-acquired infection fell from 16.9% to 9.9%. WHO now estimates that strong infection prevention programs, with hand hygiene at their center, can prevent 70% of healthcare-associated infections.
What a program needs
- Alcohol rub within reach. In one study cited by CDC, compliance rose from 38% to 63% after it was introduced.
- Education on the WHO 5 Moments and correct technique, repeated, not one-and-done.
- Skin care for staff, because sore hands get skipped.
- Leadership buy-in across the hospital. Campaigns that live in one unit tend to fade.
Most hospitals start from a low baseline: studies put typical compliance around 40%. That leaves a lot of room to prevent infections, and a lot of money to save.
- CDC. New CDC data shows decline in healthcare-associated infections. July 15, 2026 (NEJM survey of 2023 data).
- CDC. Antibiotic Resistance Threats Report 2019: MRSA fact sheet (2017 data).
- WHO. First global report on infection prevention and control. May 6, 2022.
- Pennsylvania Health Care Cost Containment Council. Hospital-Acquired Infections in Pennsylvania, Calendar Year 2006. April 2008 (PDF).
- Pittet D, et al. Effectiveness of a hospital-wide programme to improve compliance with hand hygiene. Lancet. 2000;356:1307-1312.
- Erasmus V, et al. Compliance with hand hygiene guidelines in hospital care: a systematic review. Infect Control Hosp Epidemiol. 2010;31(3):283-294.
- CDC. Clinical Safety: Hand Hygiene for Healthcare Workers.